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dc.creatorĐorđević, Nataša
dc.creatorPaunović, Milica G.
dc.creatorPeulić, Aleksandar
dc.date.accessioned2021-09-24T15:37:07Z
dc.date.available2021-09-24T15:37:07Z
dc.date.issued2017
dc.identifier.issn0944-1344
dc.identifier.urihttps://gery.gef.bg.ac.rs/handle/123456789/822
dc.description.abstractIn recent years, extremely low-frequency electromagnetic field (ELF-EMF) has received considerable attention for its potential biological effects. Numerous studies have shown the role of ELF-EMF in behaviour modulation. The aim of this study was to investigate the effect of short-term ELF-EMF (50 Hz) in the development of anxiety-like behaviour in rats through change hypothalamic oxidative stress and NO. Ten adult male rats (Wistar albino) were divided in two groups: control group-without exposure to ELF-EMF and experimental group-exposed to ELF-EMF during 7 days. After the exposure, time open field test and elevated plus maze were used to evaluate the anxiety-like behaviour of rats. Upon completion of the behavioural tests, concentrations of superoxide anion (O-2 center dot(-)), nitrite (NO2-, as an indicator of NO) and peroxynitrite (ONOO-) were determined in the hypothalamus of the animals. Obtained results show that ELF-EMF both induces anxiety-like behaviour and increases concentrations of O-2 center dot(-) and NO, whereas it did not effect on ONOO- concentration in hypothalamus of rats. In conclusion, the development of anxiety-like behaviour is mediated by oxidative stress and increased NO concentration in hypothalamus of rats exposed to ELF-EMF during 7 days.en
dc.publisherSpringer Heidelberg, Heidelberg
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173041/RS//
dc.rightsrestrictedAccess
dc.sourceEnvironmental Science and Pollution Research
dc.subjectElectromagnetic fielden
dc.subjectAnxietyen
dc.subjectNitric oxideen
dc.subjectOxidative stressen
dc.subjectHypothalamusen
dc.titleAnxiety-like behavioural effects of extremely low-frequency electromagnetic field in ratsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractЂорђевић, Наташа; Пеулић, Aлександар; Пауновић, Милица Г.;
dc.citation.volume24
dc.citation.volume24
dc.citation.issue27
dc.citation.spage21693
dc.citation.epage21699
dc.citation.rankM22
dc.identifier.wos000409962200014
dc.identifier.doi10.1007/s11356-017-9710-1
dc.identifier.pmid28756602
dc.identifier.scopus2-s2.0-85026452058
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_gery_822
dc.type.versionpublishedVersion


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