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Anxiety-like behavioural effects of extremely low-frequency electromagnetic field in rats
dc.creator | Đorđević, Nataša | |
dc.creator | Paunović, Milica G. | |
dc.creator | Peulić, Aleksandar | |
dc.date.accessioned | 2021-09-24T15:37:07Z | |
dc.date.available | 2021-09-24T15:37:07Z | |
dc.date.issued | 2017 | |
dc.identifier.issn | 0944-1344 | |
dc.identifier.uri | https://gery.gef.bg.ac.rs/handle/123456789/822 | |
dc.description.abstract | In recent years, extremely low-frequency electromagnetic field (ELF-EMF) has received considerable attention for its potential biological effects. Numerous studies have shown the role of ELF-EMF in behaviour modulation. The aim of this study was to investigate the effect of short-term ELF-EMF (50 Hz) in the development of anxiety-like behaviour in rats through change hypothalamic oxidative stress and NO. Ten adult male rats (Wistar albino) were divided in two groups: control group-without exposure to ELF-EMF and experimental group-exposed to ELF-EMF during 7 days. After the exposure, time open field test and elevated plus maze were used to evaluate the anxiety-like behaviour of rats. Upon completion of the behavioural tests, concentrations of superoxide anion (O-2 center dot(-)), nitrite (NO2-, as an indicator of NO) and peroxynitrite (ONOO-) were determined in the hypothalamus of the animals. Obtained results show that ELF-EMF both induces anxiety-like behaviour and increases concentrations of O-2 center dot(-) and NO, whereas it did not effect on ONOO- concentration in hypothalamus of rats. In conclusion, the development of anxiety-like behaviour is mediated by oxidative stress and increased NO concentration in hypothalamus of rats exposed to ELF-EMF during 7 days. | en |
dc.publisher | Springer Heidelberg, Heidelberg | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173041/RS// | |
dc.rights | restrictedAccess | |
dc.source | Environmental Science and Pollution Research | |
dc.subject | Electromagnetic field | en |
dc.subject | Anxiety | en |
dc.subject | Nitric oxide | en |
dc.subject | Oxidative stress | en |
dc.subject | Hypothalamus | en |
dc.title | Anxiety-like behavioural effects of extremely low-frequency electromagnetic field in rats | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Ђорђевић, Наташа; Пеулић, Aлександар; Пауновић, Милица Г.; | |
dc.citation.volume | 24 | |
dc.citation.volume | 24 | |
dc.citation.issue | 27 | |
dc.citation.spage | 21693 | |
dc.citation.epage | 21699 | |
dc.citation.rank | M22 | |
dc.identifier.wos | 000409962200014 | |
dc.identifier.doi | 10.1007/s11356-017-9710-1 | |
dc.identifier.pmid | 28756602 | |
dc.identifier.scopus | 2-s2.0-85026452058 | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_gery_822 | |
dc.type.version | publishedVersion |