Anxiety-like behavioural effects of extremely low-frequency electromagnetic field in rats
Само за регистроване кориснике
2017
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
In recent years, extremely low-frequency electromagnetic field (ELF-EMF) has received considerable attention for its potential biological effects. Numerous studies have shown the role of ELF-EMF in behaviour modulation. The aim of this study was to investigate the effect of short-term ELF-EMF (50 Hz) in the development of anxiety-like behaviour in rats through change hypothalamic oxidative stress and NO. Ten adult male rats (Wistar albino) were divided in two groups: control group-without exposure to ELF-EMF and experimental group-exposed to ELF-EMF during 7 days. After the exposure, time open field test and elevated plus maze were used to evaluate the anxiety-like behaviour of rats. Upon completion of the behavioural tests, concentrations of superoxide anion (O-2 center dot(-)), nitrite (NO2-, as an indicator of NO) and peroxynitrite (ONOO-) were determined in the hypothalamus of the animals. Obtained results show that ELF-EMF both induces anxiety-like behaviour and increases concentr...ations of O-2 center dot(-) and NO, whereas it did not effect on ONOO- concentration in hypothalamus of rats. In conclusion, the development of anxiety-like behaviour is mediated by oxidative stress and increased NO concentration in hypothalamus of rats exposed to ELF-EMF during 7 days.
Кључне речи:
Electromagnetic field / Anxiety / Nitric oxide / Oxidative stress / HypothalamusИзвор:
Environmental Science and Pollution Research, 2017, 24, 27, 21693-21699Издавач:
- Springer Heidelberg, Heidelberg
Финансирање / пројекти:
- Молекуларно физиолошки биомониторинг аеробних организама заснован на одређивању биохемијских биомаркера оксидационог стреса (RS-MESTD-Basic Research (BR or ON)-173041)
DOI: 10.1007/s11356-017-9710-1
ISSN: 0944-1344
PubMed: 28756602
WoS: 000409962200014
Scopus: 2-s2.0-85026452058
Колекције
Институција/група
Geografski fakultetTY - JOUR AU - Đorđević, Nataša AU - Paunović, Milica G. AU - Peulić, Aleksandar PY - 2017 UR - https://gery.gef.bg.ac.rs/handle/123456789/822 AB - In recent years, extremely low-frequency electromagnetic field (ELF-EMF) has received considerable attention for its potential biological effects. Numerous studies have shown the role of ELF-EMF in behaviour modulation. The aim of this study was to investigate the effect of short-term ELF-EMF (50 Hz) in the development of anxiety-like behaviour in rats through change hypothalamic oxidative stress and NO. Ten adult male rats (Wistar albino) were divided in two groups: control group-without exposure to ELF-EMF and experimental group-exposed to ELF-EMF during 7 days. After the exposure, time open field test and elevated plus maze were used to evaluate the anxiety-like behaviour of rats. Upon completion of the behavioural tests, concentrations of superoxide anion (O-2 center dot(-)), nitrite (NO2-, as an indicator of NO) and peroxynitrite (ONOO-) were determined in the hypothalamus of the animals. Obtained results show that ELF-EMF both induces anxiety-like behaviour and increases concentrations of O-2 center dot(-) and NO, whereas it did not effect on ONOO- concentration in hypothalamus of rats. In conclusion, the development of anxiety-like behaviour is mediated by oxidative stress and increased NO concentration in hypothalamus of rats exposed to ELF-EMF during 7 days. PB - Springer Heidelberg, Heidelberg T2 - Environmental Science and Pollution Research T1 - Anxiety-like behavioural effects of extremely low-frequency electromagnetic field in rats VL - 24 VL - 24 IS - 27 SP - 21693 EP - 21699 DO - 10.1007/s11356-017-9710-1 UR - https://hdl.handle.net/21.15107/rcub_gery_822 ER -
@article{ author = "Đorđević, Nataša and Paunović, Milica G. and Peulić, Aleksandar", year = "2017", abstract = "In recent years, extremely low-frequency electromagnetic field (ELF-EMF) has received considerable attention for its potential biological effects. Numerous studies have shown the role of ELF-EMF in behaviour modulation. The aim of this study was to investigate the effect of short-term ELF-EMF (50 Hz) in the development of anxiety-like behaviour in rats through change hypothalamic oxidative stress and NO. Ten adult male rats (Wistar albino) were divided in two groups: control group-without exposure to ELF-EMF and experimental group-exposed to ELF-EMF during 7 days. After the exposure, time open field test and elevated plus maze were used to evaluate the anxiety-like behaviour of rats. Upon completion of the behavioural tests, concentrations of superoxide anion (O-2 center dot(-)), nitrite (NO2-, as an indicator of NO) and peroxynitrite (ONOO-) were determined in the hypothalamus of the animals. Obtained results show that ELF-EMF both induces anxiety-like behaviour and increases concentrations of O-2 center dot(-) and NO, whereas it did not effect on ONOO- concentration in hypothalamus of rats. In conclusion, the development of anxiety-like behaviour is mediated by oxidative stress and increased NO concentration in hypothalamus of rats exposed to ELF-EMF during 7 days.", publisher = "Springer Heidelberg, Heidelberg", journal = "Environmental Science and Pollution Research", title = "Anxiety-like behavioural effects of extremely low-frequency electromagnetic field in rats", volume = "24, 24", number = "27", pages = "21693-21699", doi = "10.1007/s11356-017-9710-1", url = "https://hdl.handle.net/21.15107/rcub_gery_822" }
Đorđević, N., Paunović, M. G.,& Peulić, A.. (2017). Anxiety-like behavioural effects of extremely low-frequency electromagnetic field in rats. in Environmental Science and Pollution Research Springer Heidelberg, Heidelberg., 24(27), 21693-21699. https://doi.org/10.1007/s11356-017-9710-1 https://hdl.handle.net/21.15107/rcub_gery_822
Đorđević N, Paunović MG, Peulić A. Anxiety-like behavioural effects of extremely low-frequency electromagnetic field in rats. in Environmental Science and Pollution Research. 2017;24(27):21693-21699. doi:10.1007/s11356-017-9710-1 https://hdl.handle.net/21.15107/rcub_gery_822 .
Đorđević, Nataša, Paunović, Milica G., Peulić, Aleksandar, "Anxiety-like behavioural effects of extremely low-frequency electromagnetic field in rats" in Environmental Science and Pollution Research, 24, no. 27 (2017):21693-21699, https://doi.org/10.1007/s11356-017-9710-1 ., https://hdl.handle.net/21.15107/rcub_gery_822 .